Historically, Lyon has been shaped by industry. It has been home to a number of petrochemical firms along the Rhone River, in what is known as “Chemical Valley”. Though its roots lie in the silk industry, Lyon is now also specialized in sectors of excellence such as pharmaceuticals and biotechnology. One illustration of this is the creation of the Axelera and Lyonbiopôle world competitiveness clusters, which bring together and federate a number of the region’s key players.